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Acute Stress Induces Chronic Neuroinflammatory, Microglial and Behavioral Priming: A Role for Potentiated NLRP3 Inflammasome Activation

Prior exposure to acute and chronic stressors potentiates the neuroinflammatory and microglial pro-inflammatory response to subsequent immune challenges suggesting that stressors sensitize or prime microglia. Stress-induced priming of the NLRP3 inflammasome has been implicated in this priming phenom...

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Bibliografiske detaljer
Udgivet i:Brain Behav Immun
Main Authors: Frank, Matthew G., Fonken, Laura K., Watkins, Linda R., Maier, Steven F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572608/
https://ncbi.nlm.nih.gov/pubmed/32485293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.05.063
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