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Hierarchical HotNet: identifying hierarchies of altered subnetworks

MOTIVATION: The analysis of high-dimensional ‘omics data is often informed by the use of biological interaction networks. For example, protein–protein interaction networks have been used to analyze gene expression data, to prioritize germline variants, and to identify somatic driver mutations in can...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Reyna, Matthew A, Leiserson, Mark D M, Raphael, Benjamin J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129270/
https://ncbi.nlm.nih.gov/pubmed/30423088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty613
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