Cytotoxic CD8(+) T cells recognize and kill Plasmodium vivax-infected reticulocytes

Plasmodium vivax causes approximately 100 million clinical malaria cases yearly(1,2). The basis of protective immunity is poorly understood and thought to be mediated by antibodies(3,4). Cytotoxic CD8(+) T cells (CTLs) protect against other intracellular parasites by detecting parasite peptides pres...

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Udgivet i:Nat Med
Main Authors: Junqueira, Caroline, Barbosa, Camila R. R., Costa, Pedro A. C., Teixeira-Carvalho, Andréa, Castro, Guilherme, Santara, Sumit Sen, Barbosa, Rafael P., Dotiwala, Farokh, Pereira, Dhelio B., Antonelli, Lis R., Lieberman, Judy, Gazzinelli, Ricardo T.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129205/
https://ncbi.nlm.nih.gov/pubmed/30038217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0117-4
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