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γδ T cells suppress Plasmodium falciparum blood stage infection by direct killing and phagocytosis

Activated Vγδ9Vδ2 (γδ2) T lymphocytes that sense parasite-produced phosphoantigens are expanded in Plasmodium falciparum-infected patients. Although previous studies suggested that γδ2 T cells help control erythrocytic malaria, whether γδ2 T cells recognize infected red blood cells (iRBCs) was uncer...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Junqueira, Caroline, Polidoro, Rafael, Castro, Guilherme, Absalon, Sabrina, Liang, Zhitao, Santara, Sumit Sen, Crespo, Ângela, Pereira, Dhelio B., Gazzinelli, Ricardo T., Dvorin, Jeffrey D., Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906917/
https://ncbi.nlm.nih.gov/pubmed/33432229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-00847-4
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