Requirement for MUC5AC in KRAS-dependent lung carcinogenesis

With more than 150,000 deaths per year in the US alone, lung cancer has the highest number of deaths for any cancer. These poor outcomes reflect a lack of treatment for the most common form of lung cancer, non–small cell lung carcinoma (NSCLC). Lung adenocarcinoma (ADC) is the most prevalent subtype...

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Udgivet i:JCI Insight
Main Authors: Bauer, Alison K., Umer, Misha, Richardson, Vanessa L., Cumpian, Amber M., Harder, Anna Q., Khosravi, Nasim, Azzegagh, Zoulikha, Hara, Naoko M., Ehre, Camille, Mohebnasab, Maedeh, Caetano, Mauricio S., Merrick, Daniel T., van Bokhoven, Adrie, Wistuba, Ignacio I., Kadara, Humam, Dickey, Burton F., Velmurugan, Kalpana, Mann, Patrick R., Lu, Xian, Barón, Anna E., Evans, Christopher M., Moghaddam, Seyed Javad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129115/
https://ncbi.nlm.nih.gov/pubmed/30089720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120941
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