Requirement for MUC5AC in KRAS-dependent lung carcinogenesis

With more than 150,000 deaths per year in the US alone, lung cancer has the highest number of deaths for any cancer. These poor outcomes reflect a lack of treatment for the most common form of lung cancer, non–small cell lung carcinoma (NSCLC). Lung adenocarcinoma (ADC) is the most prevalent subtype...

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Pubblicato in:JCI Insight
Autori principali: Bauer, Alison K., Umer, Misha, Richardson, Vanessa L., Cumpian, Amber M., Harder, Anna Q., Khosravi, Nasim, Azzegagh, Zoulikha, Hara, Naoko M., Ehre, Camille, Mohebnasab, Maedeh, Caetano, Mauricio S., Merrick, Daniel T., van Bokhoven, Adrie, Wistuba, Ignacio I., Kadara, Humam, Dickey, Burton F., Velmurugan, Kalpana, Mann, Patrick R., Lu, Xian, Barón, Anna E., Evans, Christopher M., Moghaddam, Seyed Javad
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129115/
https://ncbi.nlm.nih.gov/pubmed/30089720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120941
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