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New derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors: Synthesis, biological testing and solubility in pharmaceutically relevant solvents

The derivatives of hydrogenated pyrido[4,3-b]indoles as potential neuroprotectors have been synthesized. The different substituents were introduced into position 8 of the carboline fragment of the molecule: methyl-, methoxy-, fluorine- and chlorine-. Biological tests have shown that all the studied...

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Vydáno v:Saudi Pharm J
Hlavní autoři: Blokhina, Svetlana, Sharapova, Angelica, Ol'khovich, Marina, Ustinov, Anatoly, Perlovich, German
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128713/
https://ncbi.nlm.nih.gov/pubmed/30202220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2018.04.003
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