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The Gramine Route to Pyrido[4,3-b]indol-3-ones – Identification of a New Cytotoxic Lead
A novel approach to 3-oxo-γ-carbolines was worked out starting from methyl indol-2-ylacetate via a gramine derivative. After quaternization, ammonia and 4-methoxybenzylamine could be inserted giving appropriate 3-oxo-γ-carbolines. Condensation with 2-chlorobenzaldehyde under microwave irradiation ga...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Österreichische Apotheker-Verlagsgesellschaft
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097496/ https://ncbi.nlm.nih.gov/pubmed/21617772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1011-11 |
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