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Predicting the Solubility of Pharmaceutical Cocrystals in Solvent/Anti-Solvent Mixtures

In this work, the solubilities of pharmaceutical cocrystals in solvent/anti-solvent systems were predicted using PC-SAFT in order to increase the efficiency of cocrystal formation processes. Modeling results and experimental data were compared for the cocrystal system nicotinamide/succinic acid (2:1...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lange, Linda, Heisel, Stefan, Sadowski, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273375/
https://ncbi.nlm.nih.gov/pubmed/27164075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21050593
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