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Defective RNA polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 pathway

Transcription by RNA polymerase III (Pol III) is an essential cellular process, and mutations in Pol III can cause neurodegenerative disease in humans. However, in contrast to Pol II transcription, which has been extensively studied, the knowledge of how Pol III is regulated is very limited. We repo...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Zheng, Wu, Catherine, Aslanian, Aaron, Yates, John R, Hunter, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128692/
https://ncbi.nlm.nih.gov/pubmed/30192228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35447
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