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The new H(2)S-releasing compound ACS94 exerts protective effects through the modulation of thiol homoeostasis
The synthesis of a new dithiolethione-cysteine ethyl ester hybrid, ACS94, its metabolites, and its effect on GSH levels in rat tissues and on the concentration of circulating H(2)S is described. ACS94 rapidly enters the cells, where it is metabolised to cysteine and the dithiolethione moiety ACS48....
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| 出版年: | J Enzyme Inhib Med Chem |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6127811/ https://ncbi.nlm.nih.gov/pubmed/30173573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1509211 |
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