Effects of Hydrogen Sulfide-releasing l-DOPA Derivatives on Glial Activation: POTENTIAL FOR TREATING PARKINSON DISEASE

The main lesion in Parkinson disease (PD) is loss of substantia nigra dopaminergic neurons. Levodopa (l-DOPA) is the most widely used therapy, but it does not arrest disease progression. Some possible contributing factors to the continuing neuronal loss are oxidative stress, including oxidation of l...

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Главные авторы: Lee, Moonhee, Tazzari, Valerio, Giustarini, Daniela, Rossi, Ranieri, Sparatore, Anna, Del Soldato, Piero, McGeer, Edith, McGeer, Patrick L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878495/
https://ncbi.nlm.nih.gov/pubmed/20368333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115261
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