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Immediate stabilization of human blood for delayed quantification of endogenous thiols and disulfides

Endogenous thiols undergo rapid and reversible oxidation to disulfides when exposed to oxidants and are, therefore, suitable biomarkers of oxidative stress. However, accurate analysis of thiols in blood is frequently compromised by their artifactual oxidation during sample manipulation, which spurio...

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Detalhes bibliográficos
Publicado no:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Giustarini, Daniela, Galvagni, Federico, Orlandini, Maurizio, Fanti, Paolo, Rossi, Ranieri
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829439/
https://ncbi.nlm.nih.gov/pubmed/26896310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2016.02.009
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