mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors

In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of synaptic innervation during postnatal development. The cognate mGlu5 receptor is absent in mature PCs and shows low expression levels in the adult cerebell...

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Publicado no:Sci Rep
Main Authors: Notartomaso, Serena, Nakao, Harumi, Mascio, Giada, Scarselli, Pamela, Cannella, Milena, Zappulla, Cristina, Madonna, Michele, Motolese, Marta, Gradini, Roberto, Liberatore, Francesca, Zonta, Micaela, Carmignoto, Giorgio, Battaglia, Giuseppe, Bruno, Valeria, Watanabe, Masahiko, Aiba, Atsu, Nicoletti, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127335/
https://ncbi.nlm.nih.gov/pubmed/30190524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31369-7
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