METHYLENE BLUE COUNTERACTS H(2)S-INDUCED CARDIAC ION CHANNEL DYSFUNCTION AND ATP REDUCTION

We have previously demonstrated that methylene blue (MB) counteracts the effects of hydrogen sulfide (H(2)S) cardiotoxicity by improving cardiomyocyte contractility and intracellular Ca(2+) homeostasis disrupted by H(2)S poisoning. In vivo, MB restores cardiac contractility severely depressed by sul...

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Veröffentlicht in:Cardiovasc Toxicol
Hauptverfasser: Cheung, Joseph Y., Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Davidyock, John M., Prado, Fabian Jana, Shanmughapriya, Santhanam, Worth, Alison M., Madesh, Muniswamy, Judenherc-Haouzi, Annick, Haouzi, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126975/
https://ncbi.nlm.nih.gov/pubmed/29603116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-018-9451-5
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