The consequences of cavity creation on the folding landscape of a repeat protein depend upon context

The effect of introducing internal cavities on protein native structure and global stability has been well documented, but the consequences of these packing defects on folding free-energy landscapes have received less attention. We investigated the effects of cavity creation on the folding landscape...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Jenkins, Kelly A., Fossat, Martin J., Zhang, Siwen, Rai, Durgesh K., Klein, Sean, Gillilan, Richard, White, Zackary, Gerlich, Grayson, McCallum, Scott A., Winter, Roland, Gruner, Sol M., Barrick, Doug, Royer, Catherine A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126725/
https://ncbi.nlm.nih.gov/pubmed/30104366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807379115
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