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Highly polarized C-terminal transition state of the leucine-rich repeat domain of PP32 is governed by local stability

The leucine-rich repeat domain of PP32 is composed of five β-strand-containing repeats anchored by terminal caps. These repeats differ in sequence but are similar in structure, providing a means to connect topology, sequence, and folding pathway selection. Through kinetic studies of PP32, we find fo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dao, Thuy Phuong, Majumdar, Ananya, Barrick, Doug
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426401/
https://ncbi.nlm.nih.gov/pubmed/25902505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412165112
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