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A second backbone: the contribution of a buried asparagine ladder to the global and local stability of a leucine-rich repeat protein

Parallel β-sheet-containing repeat proteins often display a structural motif in which conserved asparagines form a continuous ladder buried within the hydrophobic core. In such “asparagine ladders”, the asparagine side-chain amides form a repetitive pattern of hydrogen bonds with neighboring main ch...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Klein, Sean A., Majumdar, Ananya, Barrick, Doug
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184636/
https://ncbi.nlm.nih.gov/pubmed/31347358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00355
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