Synthetic switch-based baculovirus for transgene expression control and selective killing of hepatocellular carcinoma cells

Baculovirus (BV) holds promise as a vector for anticancer gene delivery to combat the most common liver cancer–hepatocellular carcinoma (HCC). However, in vivo BV administration inevitably results in BV entry into non-HCC normal cells, leaky anticancer gene expression and possible toxicity. To impro...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lin, Mei-Wei, Tseng, Yen-Wen, Shen, Chih-Che, Hsu, Mu-Nung, Hwu, Jih-Ru, Chang, Chin-Wei, Yeh, Chung-Ju, Chou, Min-Yuan, Wu, Jaw-Ching, Hu, Yu-Chen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125686/
https://ncbi.nlm.nih.gov/pubmed/29905834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky447
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