Assessment of the Additional Value of Verapamil to a Moxifloxacin and Linezolid Combination Regimen in a Murine Tuberculosis Model

The favorable treatment outcome rate for multidrug-resistant tuberculosis (MDR-TB) is only 54%, and therefore new drug regimens are urgently needed. In this study, we evaluated the activity of the combination of moxifloxacin and linezolid as a possible new MDR-TB regimen in a murine TB model and the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pieterman, Elise D., te Brake, Lindsey H. M., de Knegt, Gerjo J., van der Meijden, Aart, Alffenaar, Jan-Willem C., Bax, Hannelore I., Aarnoutse, Rob E., de Steenwinkel, Jurriaan E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125510/
https://ncbi.nlm.nih.gov/pubmed/29987154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01354-18
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