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Assessment of Bactericidal Drug Activity and Treatment Outcome in a Mouse Tuberculosis Model Using a Clinical Beijing Strain

Mycobacterium tuberculosis Beijing strains are associated with lower treatment success rates in tuberculosis (TB) patients. In contrast, laboratory strains such as H37Rv are often used in preclinical tuberculosis models. Therefore, we explored the impact of using a clinical Beijing strain on treatme...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Mourik, Bas C., de Knegt, Gerjo J., Verbon, Annelies, Mouton, Johan W., Bax, Hannelore I., de Steenwinkel, Jurriaan E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610537/
https://ncbi.nlm.nih.gov/pubmed/28739784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00696-17
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