Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice

Despite the increasing use of humanized mouse models to study new approaches of graft-versus-host disease (GVHD) prevention, the pathogenesis of xenogeneic GVHD (xGVHD) in these models remains misunderstood. The aim of this study is to describe this pathogenesis in NOD/LtSz-Prkdc(scid)IL2rγ(tm1Wjl)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ehx, Grégory, Somja, Joan, Warnatz, Hans-Jörg, Ritacco, Caroline, Hannon, Muriel, Delens, Loïc, Fransolet, Gilles, Delvenne, Philippe, Muller, Joséphine, Beguin, Yves, Lehrach, Hans, Belle, Ludovic, Humblet-Baron, Stéphanie, Baron, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125392/
https://ncbi.nlm.nih.gov/pubmed/30214443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01943
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