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Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host Disease
BACKGROUND: Sclerodermatous chronic Graft-versus-Host Disease (scl-cGVHD) is one of the most severe form of cGVHD. The Platelet-derived Grotwth Factor (PDGF) and the Transforming Growth Factor-β (TGF-β) play a significant role in the fibrosing process occurring in scl-cGVHD. This prompted us to asse...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152855/ https://ncbi.nlm.nih.gov/pubmed/27942010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167997 |
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