Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host Disease

BACKGROUND: Sclerodermatous chronic Graft-versus-Host Disease (scl-cGVHD) is one of the most severe form of cGVHD. The Platelet-derived Grotwth Factor (PDGF) and the Transforming Growth Factor-β (TGF-β) play a significant role in the fibrosing process occurring in scl-cGVHD. This prompted us to asse...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Belle, Ludovic, Fransolet, Gilles, Somja, Joan, Binsfeld, Marilène, Delvenne, Philippe, Drion, Pierre, Hannon, Muriel, Beguin, Yves, Ehx, Grégory, Baron, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152855/
https://ncbi.nlm.nih.gov/pubmed/27942010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167997
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