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Validation of a multicolor staining to monitor (phospho)STAT5 levels in regulatory T-cell subsets
BACKGROUND: Regulatory T cells (T(regs)) are key players in immune tolerance. They express the transcription factor FOXP3 and are dependent of the STAT5 signaling for their homeostasis. So far, the study of phosphorylated epitopes by flow cytometry required treating the cells with methanol, which is...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791230/ https://ncbi.nlm.nih.gov/pubmed/26657728 |
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