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Quantitative Proteomic Analysis of 2D and 3D Cultured Colorectal Cancer Cells: Profiling of Tankyrase Inhibitor XAV939-Induced Proteome

Recently there has been a growing interest in three-dimensional (3D) cell culture systems for drug discovery and development. These 3D culture systems better represent the in vivo cellular environment compared to two-dimensional (2D) cell culture, thereby providing more physiologically reliable info...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Kim, Young Eun, Jeon, Hyo Jin, Kim, Dahee, Lee, Sun Young, Kim, Ki Young, Hong, Jongki, Maeng, Pil Jae, Kim, Kwang-Rok, Kang, Dukjin
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125324/
https://ncbi.nlm.nih.gov/pubmed/30185973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31564-6
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