IL-6 mediates cross-talk between tumor cells and activated fibroblasts in the tumor microenvironment

The tumor microenvironment (TME) plays a major role in the pathogenesis of multiple cancer types, including upper-gastrointestinal (GI) cancers that currently lack effective therapeutic options. Cancer-associated fibroblasts (CAF) are an essential component of the TME, contributing to tumorigenesis...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Karakasheva, Tatiana A., Lin, Eric W., Tang, Qiaosi, Qiao, Edmund, Waldron, Todd J., Soni, Monica, Klein-Szanto, Andres J., Sahu, Varun, Basu, Devraj, Ohashi, Shinya, Baba, Kiichiro, Giaccone, Zachary T., Walker, Sarah R., Frank, David A., Wileyto, E. Paul, Long, Qi, Dunagin, Margaret C., Raj, Arjun, Diehl, J. Alan, Wong, K. K., Bass, Adam J., Rustgi, Anil K.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125177/
https://ncbi.nlm.nih.gov/pubmed/29976575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-2268
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