Circulating RIPK3 levels are associated with mortality and organ failure during critical illness

BACKGROUND. Necroptosis is a form of programmed necrotic cell death that is rapidly emerging as an important pathophysiological pathway in numerous disease states. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental mod...

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Udgivet i:JCI Insight
Main Authors: Ma, Kevin C., Schenck, Edward J., Siempos, Ilias I., Cloonan, Suzanne M., Finkelzstein, Eli J., Pabon, Maria A., Oromendia, Clara, Ballman, Karla V., Baron, Rebecca M., Fredenburgh, Laura E., Higuera, Angelica, Lee, Jin Young, Chung, Chi Ryang, Jeon, Kyeongman, Yang, Jeong Hoon, Howrylak, Judie A., Huh, Jin-Won, Suh, Gee Young, Choi, Augustine M.K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124535/
https://ncbi.nlm.nih.gov/pubmed/29997296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99692
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