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Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis

BACKGROUND. In sepsis, there may be dysregulation in programed cell death pathways, typified by apoptosis and necroptosis. Programmed cell death pathways may contribute to variability in the immune response. TRAIL is a potent inducer of apoptosis. Receptor-interacting serine/threonine protein kinase...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Schenck, Edward J., Ma, Kevin C., Price, David R., Nicholson, Thomas, Oromendia, Clara, Gentzler, Eliza Rose, Sanchez, Elizabeth, Baron, Rebecca M., Fredenburgh, Laura E., Huh, Jin-Won, Siempos, Ilias I., Choi, Augustine M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538332/
https://ncbi.nlm.nih.gov/pubmed/31045578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127143
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