Circulating RIPK3 levels are associated with mortality and organ failure during critical illness

BACKGROUND. Necroptosis is a form of programmed necrotic cell death that is rapidly emerging as an important pathophysiological pathway in numerous disease states. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental mod...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Ma, Kevin C., Schenck, Edward J., Siempos, Ilias I., Cloonan, Suzanne M., Finkelzstein, Eli J., Pabon, Maria A., Oromendia, Clara, Ballman, Karla V., Baron, Rebecca M., Fredenburgh, Laura E., Higuera, Angelica, Lee, Jin Young, Chung, Chi Ryang, Jeon, Kyeongman, Yang, Jeong Hoon, Howrylak, Judie A., Huh, Jin-Won, Suh, Gee Young, Choi, Augustine M.K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Clinical Medicine
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124535/
https://ncbi.nlm.nih.gov/pubmed/29997296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99692
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