Circulating RIPK3 levels are associated with mortality and organ failure during critical illness

BACKGROUND. Necroptosis is a form of programmed necrotic cell death that is rapidly emerging as an important pathophysiological pathway in numerous disease states. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental mod...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ma, Kevin C., Schenck, Edward J., Siempos, Ilias I., Cloonan, Suzanne M., Finkelzstein, Eli J., Pabon, Maria A., Oromendia, Clara, Ballman, Karla V., Baron, Rebecca M., Fredenburgh, Laura E., Higuera, Angelica, Lee, Jin Young, Chung, Chi Ryang, Jeon, Kyeongman, Yang, Jeong Hoon, Howrylak, Judie A., Huh, Jin-Won, Suh, Gee Young, Choi, Augustine M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124535/
https://ncbi.nlm.nih.gov/pubmed/29997296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99692
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