Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease

Aging is the strongest risk factor for Alzheimer’s disease (AD), although the underlying mechanisms remain unclear. The chromatin state, in particular through the mark H4K16ac, has been implicated in aging and thus may play a pivotal role in age-associated neurodegeneration. Here we compare the geno...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Nativio, Raffaella, Donahue, Greg, Berson, Amit, Lan, Yemin, Amlie-Wolf, Alexander, Tuzer, Ferit, Toledo, Jon B., Gosai, Sager J., Gregory, Brian D., Torres, Claudio, Trojanowski, John Q., Wang, Li-San, Johnson, F. Brad, Bonini, Nancy M., Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124498/
https://ncbi.nlm.nih.gov/pubmed/29507413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0101-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados