Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

Aging is a major risk factor for many neurodegenerative disorders. A key feature of aging biology that may underlie these diseases is cellular senescence. Senescent cells accumulate in tissues with age, undergo widespread changes in gene expression, and typically demonstrate altered, pro-inflammator...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Crowe, Elizabeth P., Tuzer, Ferit, Gregory, Brian D., Donahue, Greg, Gosai, Sager J., Cohen, Justin, Leung, Yuk Y., Yetkin, Emre, Nativio, Raffaella, Wang, Li-San, Sell, Christian, Bonini, Nancy M., Berger, Shelley L., Johnson, F. Brad, Torres, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005348/
https://ncbi.nlm.nih.gov/pubmed/27630559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00208
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