Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation

Pathologic glomerular epithelial cell (GEC) hyperplasia is characteristic of both rapidly progressive glomerulonephritis (RPGN) and subtypes of focal segmental glomerulosclerosis (FSGS). Although initial podocyte injury resulting in activation of STAT3 signals GEC proliferation in both diseases, mec...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Estrada, Chelsea C., Paladugu, Praharshasai, Guo, Yiqing, Pace, Jesse, Revelo, Monica P., Salant, David J., Shankland, Stuart J., D’Agati, Vivette D., Mehrotra, Anita, Cardona, Stephanie, Bialkowska, Agnieszka B., Yang, Vincent W., He, John C., Mallipattu, Sandeep K.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124441/
https://ncbi.nlm.nih.gov/pubmed/29925693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98214
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