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Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation

Pathologic glomerular epithelial cell (GEC) hyperplasia is characteristic of both rapidly progressive glomerulonephritis (RPGN) and subtypes of focal segmental glomerulosclerosis (FSGS). Although initial podocyte injury resulting in activation of STAT3 signals GEC proliferation in both diseases, mec...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Estrada, Chelsea C., Paladugu, Praharshasai, Guo, Yiqing, Pace, Jesse, Revelo, Monica P., Salant, David J., Shankland, Stuart J., D’Agati, Vivette D., Mehrotra, Anita, Cardona, Stephanie, Bialkowska, Agnieszka B., Yang, Vincent W., He, John C., Mallipattu, Sandeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124441/
https://ncbi.nlm.nih.gov/pubmed/29925693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98214
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