Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation

Pathologic glomerular epithelial cell (GEC) hyperplasia is characteristic of both rapidly progressive glomerulonephritis (RPGN) and subtypes of focal segmental glomerulosclerosis (FSGS). Although initial podocyte injury resulting in activation of STAT3 signals GEC proliferation in both diseases, mec...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Estrada, Chelsea C., Paladugu, Praharshasai, Guo, Yiqing, Pace, Jesse, Revelo, Monica P., Salant, David J., Shankland, Stuart J., D’Agati, Vivette D., Mehrotra, Anita, Cardona, Stephanie, Bialkowska, Agnieszka B., Yang, Vincent W., He, John C., Mallipattu, Sandeep K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124441/
https://ncbi.nlm.nih.gov/pubmed/29925693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98214
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