The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma

Resistance to current therapies still impacts a significant number of melanoma patients and can be regulated by epigenetic alterations. Analysis of global cytosine methylation in a cohort of primary melanomas revealed a pattern of early demethylation associated with overexpression of oncogenic trans...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:JCI Insight
Main Authors: Giricz, Orsi, Mo, Yongkai, Dahlman, Kimberly B., Cotto-Rios, Xiomaris M., Vardabasso, Chiara, Nguyen, Hoa, Matusow, Bernice, Bartenstein, Matthias, Polishchuk, Veronika, Johnson, Douglas B., Bhagat, Tushar D., Shellooe, Rafe, Burton, Elizabeth, Tsai, James, Zhang, Chao, Habets, Gaston, Greally, John M., Yu, Yiting, Kenny, Paraic A., Fields, Gregg B., Pradhan, Kith, Stanley, E. Richard, Bernstein, Emily, Bollag, Gideon, Gavathiotis, Evripidis, West, Brian L., Sosman, Jeffrey A., Verma, Amit K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2018
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124424/
https://ncbi.nlm.nih.gov/pubmed/30046005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120422
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