Na(V)1.1 inhibition can reduce visceral hypersensitivity

Functional bowel disorder patients can suffer from chronic abdominal pain, likely due to visceral hypersensitivity to mechanical stimuli. As there is only a limited understanding of the basis of chronic visceral hypersensitivity (CVH), drug-based management strategies are ill defined, vary considera...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Salvatierra, Juan, Castro, Joel, Erickson, Andelain, Li, Qian, Braz, Joao, Gilchrist, John, Grundy, Luke, Rychkov, Grigori Y., Deiteren, Annemie, Rais, Rana, King, Glenn F., Slusher, Barbara S., Basbaum, Allan, Pasricha, Pankaj J., Brierley, Stuart M., Bosmans, Frank
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124407/
https://ncbi.nlm.nih.gov/pubmed/29875317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121000
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