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MALDI Mass Spectrometry Imaging Reveals Heterogeneous Distribution of Tenofovir and Tenofovir Diphosphate in Colorectal Tissue of Subjects Receiving a Tenofovir-Containing Enema

Efforts to prevent human immunodeficiency virus (HIV) infection via pre-exposure prophylaxis (PrEP) include the development of anti-HIV drugs as microbicides for topical application to the mucosal sites of infection; however, although understanding the distribution profiles of these drugs in target...

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Dettagli Bibliografici
Pubblicato in:J Pharmacol Exp Ther
Autori principali: Seneviratne, Herana Kamal, Hendrix, Craig W., Fuchs, Edward J., Bumpus, Namandjé N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123665/
https://ncbi.nlm.nih.gov/pubmed/30037813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.250357
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