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Towards understanding aromatase inhibitory activity via QSAR modeling
Aromatase is a rate-limiting enzyme for estrogen biosynthesis that is overproduced in breast cancer tissue. To block the growth of breast tumors, aromatase inhibitors (AIs) are employed to bind and inhibit aromatase in order to lower the amount of estrogen produced in the body. Although a number of...
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| 出版年: | EXCLI J |
|---|---|
| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Leibniz Research Centre for Working Environment and Human Factors
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123608/ https://ncbi.nlm.nih.gov/pubmed/30190660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2018-1417 |
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