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An Effective Concentration of 5-Aza-CdR to Induce Cell Death and Apoptosis in Human Pancreatic Cancer Cell Line through Reactivating RASSF1A and Up-Regulation of Bax Genes

BACKGROUND: Promoter hyper-methylation of tumor suppressor genes is a common event that occurs in cancer. As methylation is a reversible modification, agents capable of reversing an abnormal methylation status should help to combat cancer. 5-Aza-CdR is a DNA methyl-transferase inhibitor. The present...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Iran J Med Sci
Main Authors: Nikbakht Dastjerdi, Mehdi, Azarnezhad, Asaad, Hashemibeni, Batool, Salehi, Mansour, Kazemi, Mohammad, Babazadeh, Zahra
פורמט: Artigo
שפה:Inglês
יצא לאור: Iranian Journal of Medical Sciences 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123548/
https://ncbi.nlm.nih.gov/pubmed/30214106
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