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The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines

BACKGROUND: P300 is a member of the mammalian histone acetyl transferase (HAT) family, an enzyme that acetylates histones and several non-histone proteins including P53 (the most important tumor suppressor gene) during stress, which plays an important role in the apoptosis of tumor cells. Hereby, th...

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Bibliographic Details
Main Authors: Dastjerdi, Mehdi Nikbakht, Salahshoor, Mohammad R, Mardani, Mohammad, Hashemibeni, Batool, Roshankhah, Shiva
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748634/
https://ncbi.nlm.nih.gov/pubmed/23977652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.108005
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