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Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
A family of DEDDh 3′→5′ exonucleases known as Small RNA Degrading Nucleases (SDNs) initiates the turnover of ARGONAUTE1 (AGO1)-bound microRNAs in Arabidopsis by trimming their 3′ ends. Here, we report the crystal structure of Arabidopsis SDN1 (residues 2-300) in complex with a 9 nucleotide single-st...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123492/ https://ncbi.nlm.nih.gov/pubmed/30181559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05942-7 |
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