The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1

A key event in cellular physiology is the decision between membrane biogenesis and fat storage. Phosphatidic acid (PA) is an important intermediate at the branch point of these pathways and is continuously monitored by the transcriptional repressor Opi1 to orchestrate lipid metabolism. In this study...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Hofbauer, Harald F., Gecht, Michael, Fischer, Sabine C., Seybert, Anja, Frangakis, Achilleas S., Stelzer, Ernst H.K., Covino, Roberto, Hummer, Gerhard, Ernst, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122994/
https://ncbi.nlm.nih.gov/pubmed/29941475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802027
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