The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

Maintenance of energy homeostasis depends on the highly regulated storage and release of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common metabolic disorders. CIDEA is a lipid droplet (LD)-protein enriched in brown adipocytes promoting the enlargement of LDs,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Barneda, David, Planas-Iglesias, Joan, Gaspar, Maria L, Mohammadyani, Dariush, Prasannan, Sunil, Dormann, Dirk, Han, Gil-Soo, Jesch, Stephen A, Carman, George M, Kagan, Valerian, Parker, Malcolm G, Ktistakis, Nicholas T, Klein-Seetharaman, Judith, Dixon, Ann M, Henry, Susan A, Christian, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755750/
https://ncbi.nlm.nih.gov/pubmed/26609809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07485
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