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A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase

Regulation of membrane lipid composition is crucial for many aspects of cell growth and development. Lipins, a novel family of phosphatidate (PA) phosphatases that generate diacylglycerol (DAG) from PA, are emerging as essential regulators of fat metabolism, adipogenesis, and organelle biogenesis. T...

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Detalhes bibliográficos
Main Authors: Karanasios, Eleftherios, Han, Gil-Soo, Xu, Zhi, Carman, George M., Siniossoglou, Symeon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955120/
https://ncbi.nlm.nih.gov/pubmed/20876142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007974107
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