HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties

The biological properties of pancreatic cancer stem cells (PCSCs) remain incompletely defined and the central regulators are unknown. By bioinformatic analysis of a human PCSC-enriched gene signature, we identified the transcription factor HNF1A as a putative central regulator of PCSC function. Leve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Abel, Ethan V, Goto, Masashi, Magnuson, Brian, Abraham, Saji, Ramanathan, Nikita, Hotaling, Emily, Alaniz, Anthony A, Kumar-Sinha, Chandan, Dziubinski, Michele L, Urs, Sumithra, Wang, Lidong, Shi, Jiaqi, Waghray, Meghna, Ljungman, Mats, Crawford, Howard C, Simeone, Diane M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Cancer Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122955/
https://ncbi.nlm.nih.gov/pubmed/30074477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33947
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