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The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer

BACKGROUND: Pancreatic cancer stem cells (CSCs) represent a small subpopulation of pancreatic cancer cells that have the capacity to initiate and propagate tumor formation. However, the mechanisms by which pancreatic CSCs are maintained are not well understood or characterized. METHODS: Expression o...

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Detalhes bibliográficos
Main Authors: Abel, Ethan V., Kim, Edward J., Wu, Jingjiang, Hynes, Mark, Bednar, Filip, Proctor, Erica, Wang, Lidong, Dziubinski, Michele L., Simeone, Diane M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960140/
https://ncbi.nlm.nih.gov/pubmed/24647545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091983
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