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D-Fructose-based spiro-fused PHOX ligands: synthesis and application in enantioselective allylic alkylation

Phosphinooxazoline (PHOX) ligands are an important class of ligands in asymmetric catalysis. We synthesized ten novel D-fructose-derived spiro-fused PHOX ligands with different steric and electronic demand. The application of two of them was tested in asymmetric allylic alkylation. The ligands are p...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Imrich, Michael R, Kraft, Jochen, Maichle-Mössmer, Cäcilia, Ziegler, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122323/
https://ncbi.nlm.nih.gov/pubmed/30202461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.182
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