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Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation

Proton beam irradiation promises therapeutic utility in the management of uveal melanoma. Calcitriol (1,25(OH)(2)D(3))—the biologically active metabolite of vitamin D(3)—and its precursor, calcidiol (25(OH)D(3)), exert pleiotropic effects on melanoma cells. The aim of the study was to evaluate the e...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Podgorska, Ewa, Drzal, Agnieszka, Matuszak, Zenon, Swakon, Jan, Slominski, Andrzej, Elas, Martyna, Urbanska, Krystyna
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122082/
https://ncbi.nlm.nih.gov/pubmed/30065179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082236
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