Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation

Proton beam irradiation promises therapeutic utility in the management of uveal melanoma. Calcitriol (1,25(OH)(2)D(3))—the biologically active metabolite of vitamin D(3)—and its precursor, calcidiol (25(OH)D(3)), exert pleiotropic effects on melanoma cells. The aim of the study was to evaluate the e...

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Publicat a:Int J Mol Sci
Autors principals: Podgorska, Ewa, Drzal, Agnieszka, Matuszak, Zenon, Swakon, Jan, Slominski, Andrzej, Elas, Martyna, Urbanska, Krystyna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122082/
https://ncbi.nlm.nih.gov/pubmed/30065179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082236
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