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Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low–LET Proton Beam Irradiation

Proton beam irradiation promises therapeutic utility in the management of uveal melanoma. Calcitriol (1,25(OH)(2)D(3))—the biologically active metabolite of vitamin D(3)—and its precursor, calcidiol (25(OH)D(3)), exert pleiotropic effects on melanoma cells. The aim of the study was to evaluate the e...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Podgorska, Ewa, Drzal, Agnieszka, Matuszak, Zenon, Swakon, Jan, Slominski, Andrzej, Elas, Martyna, Urbanska, Krystyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122082/
https://ncbi.nlm.nih.gov/pubmed/30065179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082236
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